Holiday Inn Express & Suites Houston S Medical Center Area by IHG

9300 S Main Street, Houston, TX 77025 US near Exit 1c on I-610 (~0.8mi)
View Map Reservations: +1-800-219-2797
2.5 Star Property In Houston (Braeswood Place)
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Very Good
4.0/5

Based on 745 guest reviews

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  • Pool umbrellas
  • Pool hoist on site
  • Wheelchair-accessible pool
  • Free WiFi
  • Number of outdoor pools - 1
  • 24-hour fitness facilities
  • Free continental breakfast
  • Free breakfast
  • Smoke-free property
Select Your Room:
07/30/2026 - 07/31/2026
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1 bookings in the last 48 hours

Standard prices by room type for the next 60 days

Rates shown are nightly rates before taxes and do not necessarily reflect all discounts available. The chart provides the cheapest public rates available by room type.

Verified Reviews of Holiday Inn Express & Suites Houston S Medical Center Area by IHG

Below are the verified reviews from guests that we have booked recently:
"Good Hotel & Location"
Overall Score3.0/ 5
Overall was up to expectations. We will still use again for the price and convenient location to medical appointments.
(Individual traveler, booked 1 room), from US flag
17-Jan-2026 Verified Review, stayed from Wed Jan 14 to Thu Jan 15 2026 at a $140.99 average nightly rate.
"Customer satisfaction"
Overall Score5.0/ 5
Kimberly Front Desk Clerk made sure customer was satisfied and feel comfortable and welcome! She made sure customer enjoyed he/she stay. She made the stay at the hotel worth stay. Kimberly is a great asset to your company! Kimberly keep up the great work and Holiday Inn keep the customer service going! I will recommend my family and friends to your hotel when visiting the Houston area!
(Individual traveler, booked 1 room), from US flag
18-Dec-2025 Verified Review, stayed from Tue Dec 16 to Fri Dec 19 2025 at a $114.99 average nightly rate.
"Exceptional"
Overall Score5.0/ 5
We arrived earlier than check in time but they still had a room available. The consideration of the staff, the cleanliness of not just the rooms but the entire hotel is outstanding. The price was good, the employees were good and the hotel was good! You will never go wrong by staying here.
(Individual traveler, booked 1 room), from US flag
16-Sep-2025 Verified Review, stayed from Tue Sep 16 to Wed Sep 17 2025 at a $116.00 average nightly rate.
"Clean, inviting, quiet, great breakfast."
Overall Score5.0/ 5
We’ll be back.
(Individual traveler, booked 1 room), from US flag
31-Aug-2025 Verified Review, stayed from Thu Aug 28 to Fri Aug 29 2025 at a $110.99 average nightly rate.
"Very good experience!"
Overall Score5.0/ 5
Very professional and friendly staff. Clean, neat and nice hotel.
(Individual traveler, booked 1 room), from US flag
15-Jun-2025 Verified Review, stayed from Tue Jun 10 to Fri Jun 13 2025 at a $121.00 average nightly rate.
"Excellent Stay!"
Overall Score5.0/ 5
Excellent First Stay! Clean and Comfortable. Will be back.
(Individual traveler, booked 1 room), from US flag
16-May-2025 Verified Review, stayed from Tue May 13 to Wed May 14 2025 at a $140.99 average nightly rate.
"Excellent Accommodations"
Overall Score5.0/ 5
My room was clean, quiet and comfortable. I would stay again.
(Individual traveler, booked 1 room), from US flag
19-Apr-2025 Verified Review, stayed from Wed Apr 16 to Thu Apr 17 2025 at a $219.99 average nightly rate.
"Great Hotel Experience"
Overall Score5.0/ 5
Great staff and clean rooms.
(Individual traveler, booked 1 room), from US flag
13-Mar-2025 Verified Review, stayed from Sun Mar 09 to Thu Mar 13 2025 at a $228.49 average nightly rate.
"Very Good"
Overall Score5.0/ 5
Our stay was very good.
(Individual traveler, booked 1 room), from US flag
27-Feb-2025 Verified Review, stayed from Wed Feb 26 to Thu Feb 27 2025 at a $153.99 average nightly rate.

Summary of Verified Reviews

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Property Description

A stay at Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG places you in the heart of Houston, within a 15-minute walk of NRG Stadium and NRG Park. This hotel is 2.5 mi (4.1 km) from MD Anderson Cancer Center and 2.9 mi (4.6 km) from Rice University.

A complimentary continental breakfast is served on weekdays from 6:00 AM to 9:30 AM and on weekends from 6:30 AM to 10:00 AM.

Make yourself at home in one of the 146 air-conditioned rooms featuring refrigerators and LCD televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Private bathrooms with shower/tub combinations feature hair dryers and toothbrushes and toothpaste. Conveniences include safes and desks, as well as phones with free local calls.

Distances are displayed to the nearest 0.1 mile and kilometer.

NRG Park - 0.6 km / 0.3 mi
NRG Stadium - 1.2 km / 0.7 mi
NRG Astrodome - 1.8 km / 1.1 mi
NRG Center - 1.8 km / 1.1 mi
NRG Arena - 2 km / 1.2 mi
The Woman's Hospital of Texas - 3 km / 1.8 mi
Baylor St. Luke's Medical Center-McNair Campus - 3.7 km / 2.3 mi
Texas Children's Hospital - 3.8 km / 2.4 mi
CHI St. Luke's Health-Baylor St. Luke's Medical Center - 3.8 km / 2.4 mi
Chi St. Lukes Health Baylor College Of Medicine Medical Center - 3.9 km / 2.4 mi
Houston Methodist Hospital - 4 km / 2.5 mi
MD Anderson Cancer Center - 4.1 km / 2.5 mi
Hermann Park - 4.1 km / 2.5 mi
Main Street Theater - Rice Village - 4.6 km / 2.9 mi
Memorial Hermann Hospital - 4.7 km / 2.9 mi

The nearest airports are:
Houston William Hobby Airport (HOU) - 20.1 km / 12.5 mi
Houston, TX (EFD-Ellington Field) - 36.6 km / 22.7 mi
George Bush Intercontinental Airport (IAH) - 48.2 km / 29.9 mi

The preferred airport for Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG is Houston William Hobby Airport (HOU).

Featured amenities include a 24-hour business center, express check-in, and express check-out. Planning an event in Houston? This hotel has 675 square feet (63 square meters) of space consisting of conference space and 2 meeting rooms. Free self parking is available onsite.

Be sure to enjoy recreational amenities including an outdoor pool and a 24-hour fitness center. Additional amenities at this hotel include complimentary wireless internet access, gift shops/newsstands, and a banquet hall.

Amenities / Features

  • Check In: 3:00 PM
  • Check Out: 12:00 PM
  • Minimum age of oldest guest: 21
  • Dry cleaning/laundry service
  • Gift shops or newsstand
  • Wheelchair accessible (may have limitations)
  • Banquet hall
  • Vending machine
  • Wheelchair-accessible van parking
  • Outdoor furniture
  • Express check-in
  • Pool umbrellas
  • Number of meeting rooms - 2
  • Conference space size (meters) - 63
  • Pool hoist on site
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible fitness center
  • Wheelchair-accessible pool
  • Free WiFi
  • Wheelchair-accessible public washroom
  • Number of outdoor pools - 1
  • 24-hour fitness facilities
  • Free continental breakfast
  • Total number of rooms - 146
  • Number of floors - 4
  • Professional property host/manager
  • LGBTQIA+ friendly
  • No rollaway/extra beds available
  • Off-street parking
  • Luggage storage
  • Express check-out
  • Free breakfast
  • Visual alarms in hallways
  • Coin laundry on site
  • Handrails in stairways
  • Multilingual staff
  • 24-hour front desk
  • Wheelchair-accessible meeting spaces/business center
  • Daily
  • Smoke-free property
  • Safe-deposit box at front desk
  • Laundry facilities
  • Free self parking
  • Conference space
  • Pool sun loungers
  • ATM/banking
  • Conference space size (feet) - 675
  • 24-hour business center

Airport & Shuttle Information

George Bush Intercontinental Airport (30 miles), William P. Hobby Airport (15 miles)

Local Shuttle Info: Guests planning to visit any of the facilities within the medical center will find our hotel shuttle for our medical guests very convenient, as we will happily transport you to and from your appointments/meetings.

Breakfast Information

We offer a complimentary hot breakfast buffet 7 days a week

Pet Friendly?

Service animals complying with ADA Title lll regulations are allowed.

Service animals are allowed

Service animals are exempt from fees/restrictions

Pets not allowed

No pets allowed

Parking Info

Complimentary Self Parking

Internet / WiFI

Free secure Wi-Fi throughout the entire hotel!

Misc Fees / Policies

  • Early check-in is available for a fee (subject to availability)
  • Late check-out is available for a fee (subject to availability)

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Destination fee: USD 0.81 per accommodation, per night

We have included all charges provided to us by the property.

  • Pool access available from 10 AM to 10 PM.
  • Cashless payment methods are available for all transactions.
  • Contactless check-out is available.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Cleaning Policies

Hand sanitizer stations available throughout the hotel; Occupied rooms are serviced upon request only; Public areas are cleaned and sanitized every hour; Safe guard at he front desk as well as sneeze guards in breakfast area.

Contactless check-out is available

Cashless transactions are available

Property follows a brand or regulatory agency's sanitization guidelines Clean Promise (IHG)

About Holiday Inn Express

  • Free Express Start Breakfast
  • Have their own 100% Arabica Smart Roast Coffee
  • Free high-speed internet service in every room
  • eHost Online Concierge Service where guests can learn about hotel amenities, major airlines nearby, up-to-date local weather and even car rental services
  • Perfect for the business traveler on the go, Holiday Inn Express offers 24/7 hours & photocopy services

The Holiday Inn Express highlights above are subject to change without notice.

Seasonality and Projections at Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

Rate fluctuations of Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

The graph above is fluctuations of room rates for both our group rates and the lowest online individual prices our system could find at the time the group offer was placed. The best group/meeting rate displayed is 65.2% in the month of July 2026 and the highest average individual rate is $363 in the month of April 2024. This chart will show past seasonality and also project future months. If you are flexible with dates, you may want to consider staying at Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG in a month when rates are lower.

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