Hampton Inn & Suites Lake City

450 SW Florida Gateway Drive, Lake City, FL 32024 US near Exit 427 on I-75 (~0.3mi)
View Map Reservations: +1-800-219-2797
2.5 Star Property Near Lake City Medical Center
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Very Good
4.0/5

Based on 479 guest reviews

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  • Free full breakfast
  • Free WiFi
  • Number of outdoor pools - 1
  • Free breakfast
  • Fitness facilities
  • Wheelchair-accessible pool
  • Stair-free path to entrance
  • Smoke-free property
  • Free self parking
Select Your Room:
08/14/2026 - 08/15/2026
Searching all hotel inventory networks
10 bookings in the last 48 hours

Standard prices by room type for the next 60 days

Rates shown are nightly rates before taxes and do not necessarily reflect all discounts available. The chart provides the cheapest public rates available by room type.

Verified Reviews of Hampton Inn & Suites Lake City

Below are the verified reviews from guests that we have booked recently:
"Nice clean stay"
Overall Score4.0/ 5
Hamptons’s are a very clean hotel. From its lobby, to our room on the 3rd floor with new carpet. We were met by friendly, helpful staff at the front desk. This hotel is always our place to stop enroute from Texas to southern Florida.
(Individual traveler, booked 1 room), from US flag
12-May-2026 Verified Review, stayed from Mon May 11 to Tue May 12 2026 at a $166.99 average nightly rate.
"Excellent advice and service"
Overall Score5.0/ 5
Excellent Hampton Inn.
(Individual traveler, booked 1 room), from US flag
20-Mar-2026 Verified Review, stayed from Fri Mar 20 to Sat Mar 21 2026 at a $225.99 average nightly rate.
"Convenient stop off point"
Overall Score5.0/ 5
This hotel is well positioned off expressway, with several great restaurants in the area.
(Individual traveler, booked 1 room), from US flag
26-Jan-2026 Verified Review, stayed from Sun Jan 25 to Mon Jan 26 2026 at a $139.06 average nightly rate.
"Excellent"
Overall Score5.0/ 5
Very clean and people friendly.
(Individual traveler, booked 1 room), from US flag
04-Jan-2026 Verified Review, stayed from Fri Jan 02 to Sat Jan 03 2026 at a $136.22 average nightly rate.
"Very good checking in and room"
Overall Score4.0/ 5
(Individual traveler, booked 1 room), from US flag
01-Nov-2025 Verified Review, stayed from Fri Oct 31 to Sat Nov 01 2025 at a $208.99 average nightly rate.
"Excellent hotel"
Overall Score5.0/ 5
Great stay. Employees were very friendly and professional. Room was really nice and clean. We love Hampton Inn, we always stay there when we travel!
(Individual traveler, booked 1 room), from US flag
27-Oct-2025 Verified Review, stayed from Sun Oct 26 to Mon Oct 27 2025 at a $119.00 average nightly rate.
"Nice Place."
Overall Score5.0/ 5
Great Place.
(Individual traveler, booked 1 room), from US flag
03-Sep-2025 Verified Review, stayed from Sun Aug 31 to Mon Sep 01 2025 at a $122.99 average nightly rate.
"Hotel Joy"
Overall Score5.0/ 5
Hampton Inn was the best experience ever! The rooms were spacious, beds comfortable, the pool was perfect, the breakfast was delicious and EVERYONE was so nice! We will come here every time we travel back and forth down south. This was the best Hampton Inn!
(Group coordinator, booked 2 rooms), from US flag
27-Jun-2025 Verified Review, stayed from Tue Jun 24 to Wed Jun 25 2025 at a $114.00 average nightly rate.
"Road Trip"
Overall Score5.0/ 5
Wonderful
(Individual traveler, booked 1 room), from US flag
21-Jun-2025 Verified Review, stayed from Wed Jun 18 to Thu Jun 19 2025 at a $130.99 average nightly rate.
"Highly Recommend!"
Overall Score5.0/ 5
Very nice hotel with excellent customer service. Rooms were clean and comfortable. Highly recommend this hotel!
(Individual traveler, booked 1 room), from US flag
08-Jun-2025 Verified Review, stayed from Fri Jun 06 to Sat Jun 07 2025 at a $166.99 average nightly rate.
"Prompt. Helpful. Polite."
Overall Score5.0/ 5
Prompt. Helpful. Polite.
(Individual traveler, booked 1 room), from US flag
08-Apr-2025 Verified Review, stayed from Tue Apr 08 to Wed Apr 09 2025 at a $156.99 average nightly rate.
"Good"
Overall Score5.0/ 5
Our room was great, the staff was very kind. We had lost a loved one, thier kindness was appreciated.
(Individual traveler, booked 1 room), from US flag
16-Mar-2025 Verified Review, stayed from Wed Mar 12 to Thu Mar 13 2025 at a $184.99 average nightly rate.
"Friendly staff, very clean, great breakfast."
Overall Score5.0/ 5
We will stop here again when traveling!
(Individual traveler, booked 1 room), from US flag
15-Mar-2025 Verified Review, stayed from Thu Mar 13 to Fri Mar 14 2025 at a $161.99 average nightly rate.

Summary of Verified Reviews

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Property Description

A stay at Hampton Inn & Suites Lake City places you in the heart of Lake City, within a 5-minute drive of Regal UA Cinema 90 and Fresenius Medical Care at Lake City Medical Center. This hotel is 1 mi (1.7 km) from Lake City Medical Center and 1.5 mi (2.4 km) from Lake City Mall.

A complimentary full breakfast is served daily from 6:00 AM to 10:00 AM.

Make yourself at home in one of the 89 guestrooms featuring refrigerators and flat-screen televisions. Complimentary wired and wireless internet access keeps you connected, and satellite programming provides entertainment. Private bathrooms have complimentary toiletries and hair dryers. Conveniences include laptop-compatible safes and desks, as well as phones with free local calls.

Distances are displayed to the nearest 0.1 mile and kilometer.

Fresenius Medical Care at Lake City Medical Center - 1.6 km / 1 mi
Lake City Medical Center - 1.7 km / 1.1 mi
Regal UA Cinema 90 - 2.1 km / 1.3 mi
Lake Shore Primary Care West - 2.4 km / 1.5 mi
Lake City Mall - 2.5 km / 1.5 mi
Southside Sports Complex - 4.6 km / 2.8 mi
Southside Recreation Complex - 4.7 km / 2.9 mi
Lake City Columbia County Historical Museum - 6.4 km / 4 mi
Columbia County Courthouse - 6.4 km / 4 mi
Lake City Veterans Affairs Medical Center - 6.4 km / 4 mi
Epiphany Catholic Church - 6.7 km / 4.2 mi
Lake DeSoto Farmers Market - 7.2 km / 4.5 mi
Florida Department of Transportation - 7.2 km / 4.5 mi
Pine Grove Baptist Church - 9.3 km / 5.8 mi
North Florida Speedway - 11.6 km / 7.2 mi

The preferred airport for Hampton Inn & Suites Lake City is Gainesville Regional Airport (GNV) - 76 km / 47.2 mi

Featured amenities include a 24-hour business center, express check-out, and a 24-hour front desk. Planning an event in Lake City? This hotel has 800 square feet (74 square meters) of space consisting of conference space and a meeting room. Free self parking is available onsite.

Take advantage of recreational opportunities offered, including an outdoor pool, a fitness center, and in-room fitness. Additional features at this hotel include complimentary wireless internet access, gift shops/newsstands, and a television in a common area.

Amenities / Features

  • Check In: 3:00 PM
  • Check Out: 12:00 PM
  • Minimum age of oldest guest: 21
  • Gift shops or newsstand
  • Free full breakfast
  • Number of meeting rooms - 1
  • Conference space size (meters) - 74
  • Sailing nearby
  • Free WiFi
  • Number of outdoor pools - 1
  • Braille or raised signage
  • Water skiing nearby
  • Wheelchair accessible parking
  • No accessible shuttle
  • Hunting nearby
  • Free breakfast
  • Parasailing nearby
  • Water dispenser
  • Electric car charging station
  • Wheelchair-accessible meeting spaces/business center
  • Daily
  • Ecotours nearby
  • Coffee/tea in common areas
  • Laundry facilities
  • Rafting nearby
  • Elevator
  • Fitness facilities
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible van parking
  • Year Built - 2006
  • Total number of rooms - 89
  • Number of floors - 5
  • Professional property host/manager
  • LGBTQIA+ friendly
  • No rollaway/extra beds available
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible registration desk
  • Windsurfing nearby
  • Television in common areas
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Well-lit path to entrance
  • Picnic area
  • Stair-free path to entrance
  • Off-street parking
  • Luggage storage
  • Express check-out
  • Business center
  • 24-hour front desk
  • Personal motorized watercraft on site
  • Golfing nearby
  • Smoke-free property
  • Hiking/biking trails nearby
  • Surfing/bodyboarding nearby
  • Free self parking
  • Kayaking nearby
  • Conference space
  • Terrace
  • Pool sun loungers
  • Wheelchair accessible path of travel
  • Conference space size (feet) - 800
  • 24-hour business center

Breakfast Information

We have a hot breakfast everyday and is included with the price of the room. There's a special everyday. Then we have cereal, waffles, and etc

Pet Friendly?

Service animals complying with ADA Title lll regulations are allowed.

Maximum number of pets per room 2

Only dogs and cats are allowed

Service animals are allowed

Service animals are exempt from fees/restrictions

Pets allowed

Not Pet Friendly

Misc Fees / Policies

  • Pet fee: USD 75 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

  • Pool access available from 9:00 AM to 10:00 PM.
  • The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.
  • Contactless check-in and contactless check-out are available.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Cleaning Policies

Contactless check-in is available

Contactless check-out is available

Essential workers only - NO

About Hampton Inn

  • All US locations offer coffee & tea in the lobby at no cost
  • Free Hot Breakfast serving fresh-baked waffles and oatmeal with toppings
  • Offer 'On the Run' breakfast bags during the week if you're in a hurry
  • Free daily newspaper on weekdays

The Hampton Inn highlights above are subject to change without notice.

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